Incidence And Risk Factors Of Osteoporotic Fracture In RA Patients: A Multicenter Study Of The Frax And Who Criteria

摘要

Case reportRecently some studies revealed that low vitamin D level is associated withincreasing risk of type 1 diabetes mellitus, cardiovascular diseases,neurodegenerative diseases, and cancer. The importance of vitamin D is onthe rise. Therefore, people have interest in using vitamin D supplements.However, overdose of vitamin D could cause serious adverse effects. Thisstudy shows a case of vitamin D overdose resulting hypercalcemia.There is no absolute reference of intake dose of vitamin D that can causetoxic result. Up to 10,000 IU daily has been considered safe in a healthypopulation. The Institute of Medicine recommended dose varies from 800to 4,000IU per day according to age. Some case reports showed that hypercalcemia and acute kidney injury were due to overdose vitamin D.We report a case of a 36-year-old type 1 diabetic female with chronickidney disease who took 50,000 IU of vitamin D3 (cholecalciferol) for 2months.