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A Case of Type I Hepatorenal Syndrome Treated with Vasopressin

机译:加压素治疗I型肝肾综合征1例

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Hepatorenal syndrome (HRS) is a grave complication of end-stage liver disease and is associated with a very high mortality. This case report described a 42-year-old female with advanced alcohol-induced cirrhosis who developed HRS that was initially treated with Midodrine and Octreotide but renal function continued to deteriorate. Vasopressin therapy was added and HRS was successfully reversed. There are few data available on the use of vasopressin for HRS and this case supports its use in treatment of HRS, particularly in countries where the more widely studied Terlipressin is unavailable. This case also demonstrates that a patient failing one medical therapy for HRS may respond to an alternative or adjunctive therapy. Therefore, this should be attempted to increase the patient’s chance of survival.
机译:肝肾综合征(HRS)是晚期肝病的严重并发症,并且死亡率很高。该病例报告描述了一名患有酒精性肝硬化的42岁女性,其发展为HRS,最初接受米多君和奥曲肽治疗,但肾功能持续恶化。增加了加压素治疗,成功逆转了HRS。关于使用血管加压素治疗HRS的可用数据很少,这种情况支持将其用于HRS的治疗,特别是在没有更广泛研究的特利加压素的国家中。该案例还表明,对HRS进行一种药物治疗失败的患者可能会对替代治疗或辅助治疗产生反应。因此,应尝试增加患者的生存机会。

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