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Low Case Finding Among Men and Poor Viral Load Suppression Among Adolescents Are Impeding Namibia’s Ability to Achieve UNAIDS 90-90-90 Targets

机译:男性病例低发,青少年病毒载量抑制不良,阻碍了纳米比亚实现联合国艾滋病规划署90-90-90目标的能力

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BackgroundIn 2015, Namibia implemented an Acceleration Plan to address the high burden of HIV (13.0% adult prevalence and 216 311 people living with HIV [PLHIV]) and achieve the UNAIDS 90-90-90 targets by 2020. We provide an update on Namibia’s overall progress toward achieving these targets and estimate the percent reduction in HIV incidence since 2010.MethodsData sources include the 2013 Namibia Demographic and Health Survey (2013 NDHS), the national electronic patient monitoring system, and laboratory data from the Namibian Institute of Pathology. These sources were used to estimate (1) the percentage of PLHIV who know their HIV status, (2) the percentage of PLHIV on antiretroviral therapy (ART), (3) the percentage of patients on ART with suppressed viral loads, and (4) the percent reduction in HIV incidence.ResultsIn the 2013 NDHS, knowledge of HIV status was higher among HIV-positive women 91.8% (95% confidence interval [CI], 89.4%–93.7%) than HIV-positive men 82.5% (95% CI, 78.1%–86.1%). At the end of 2016, an estimated 88.3% (95% CI, 86.3%–90.1%) of PLHIV knew their status, and 165 939 (76.7%) PLHIV were active on ART. The viral load suppression rate among those on ART was 87%, and it was highest among ≥20-year-olds (90%) and lowest among 15–19-year-olds (68%). HIV incidence has declined by 21% since 2010.ConclusionsWith 76.7% of PLHIV on ART and 87% of those on ART virally suppressed, Namibia is on track to achieve UNAIDS 90-90-90 targets by 2020. Innovative strategies are needed to improve HIV case identification among men and adherence to ART among youth.
机译:背景信息2015年,纳米比亚实施了一项加速计划,以解决艾滋病毒的沉重负担(成年人患病率为13.0%,艾滋病毒感染者人数为216311人),并在2020年之前实现联合国艾滋病规划署90-90-90的目标。方法目标数据来源包括2013年纳米比亚人口与健康调查(2013 NDHS),国家电子患者监测系统以及纳米比亚病理学研究所的实验室数据。这些来源用于估计(1)了解其HIV状况的PLHIV的百分比,(2)抗逆转录病毒疗法(ART)的PLHIV的百分比,(3)病毒载量受到抑制的ART的患者的百分比,以及(4)结果在2013年NDHS中,HIV阳性女性的HIV状况知识高出91.8%(95%置信区间[CI],89.4%–93.7%),高于HIV阳性男性82.5%(95%)。 %CI,78.1%–86.1%)。到2016年底,估计有88.3%(95%CI,86.3%–90.1%)的艾滋病毒感染者知道自己的状况,并且有165939人(76.7%)的艾滋病毒感染者活跃于ART。接受抗逆转录病毒治疗的患者的病毒载量抑制率为87%,在≥20岁的人群中最高(90%),在15-19岁的人群中最低(68%)。自2010年以来,艾滋病毒的发病率已下降了21%。结论随着抗病毒治疗的76.7%的艾滋病毒感染者和被病毒抑制的87%的艾滋病毒感染者,纳米比亚有望在2020年之前实现联合国艾滋病规划署90-90-90的目标。需要采取创新战略来改善艾滋病毒在男性中进行病例鉴定,在青年中遵守抗逆转录病毒疗法。

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