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Bacteriological Profile of ESBL Producing Bacteria With Their Antibiotic Resistance Pattern

机译:ESBL产生细菌及其耐药模式的细菌学概况

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Background: Extended Spectrum Beta-Lactamase (ESBL) can cause infections, such as kidney infections, wound infections or in severe cases, blood infection. If a patient is prone to infection and the infection is caused by ESBLs, it can be more difficult to treat, because many of the commonly used antibiotics will not work against ESBLs. Materials and Method: This descriptive cross-sectional study was carried out to evaluate samples submitted for culture and sensitivity at Clinical Laboratory of North Bengal Medical College Hospital, Sirajganj the general objective identify the causative organisms and their antimicrobial resistance pattern. Results: Majority of subjects (37.5%) were from 46-60 years age group. ESBL resistance was significantly related with age groups and educational status. Resistance was not related with gender distribution, occupation, family size and yearly family income. Detection rate of ESBL production among Pseudomonas spp were (91.67 %), followed by Klebsiella spp. (83.33 %), Proteus spp. (69.49%), Esch. Coli (64.42 %) and others (82.35 %). Aztreonam, Ampicillin, Amoxyclave and Piperacillin were more resistant antibiotics against ESBL producing organisms.
机译:背景:超广谱β-内酰胺酶(ESBL)可以引起感染,例如肾脏感染,伤口感染或在严重情况下会引起血液感染。如果患者易于感染,并且感染是由ESBLs引起的,则治疗起来可能会更加困难,因为许多常用的抗生素将无法抵抗ESBLs。材料和方法:该描述性横断面研究旨在评估在Sirajganj的北孟加拉医学院医院临床实验室中提交的培养物和敏感性样品,其总体目的是确定病原性微生物及其耐药性模式。结果:大多数受试者(37.5%)来自46-60岁年龄组。 ESBL抵抗力与年龄组和教育程度显着相关。抵抗力与性别分布,职业,家庭规模和家庭年收入无关。假单胞菌中ESBL产生的检出率为(91.67%),其次是克雷伯菌。 (83.33%),变形杆菌属。 (69.49%),埃施。大肠杆菌(64.42%)和其他(82.35%)。 Aztreonam,氨苄青霉素,Amoxyclave和Piperacillin是对产生ESBL的生物更有抵抗力的抗生素。

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