The acute, sub-acute and chronic patients of schistosomiasis japonica reacted to the urine precipitin reaction. The antigen in urine is easy to change by heat and putrefaction. It is not clear what substance participates in this phenomenon, but it is presumable that the substance may be thermolabil and nondialyzable.The urine precipitin reaction may be used for the assessment of cure. Animal experiments showed the fact that after the reaction had become negative, the worm was not found any more.This reaction may be used for early diagnosis for schistosomiasis. One of the acute cases showed a positive reaction to this reaction test within one month after the infection. In the animal experiment the reaction changed to be positive as early as on the first week after the infection.
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