What causes a small increase in radiographic progression in rheumatoid arthritis patients tapering TNF inhibitors?

Frank H J van den Hoogen; Robert B M Landewé; Noortje van Herwaarden; Alfons A den Broeder; Chantal A M Bouman; Aatke van der Maas

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What causes a small increase in radiographic progression in rheumatoid arthritis patients tapering TNF inhibitors?

机译：是什么导致逐渐减少TNF抑制剂的类风湿关节炎患者的放射学进展略有增加？

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Abstract Objective In a randomised controlled trial investigating tapering of TNF inhibitors (TNFi) compared with usual care (UC) in rheumatoid arthritis patients, minimal radiographic progression was more frequent in patients who attempted tapering. Poss

机译：摘要目的在一项针对风湿性关节炎患者与常规治疗（UC）相比逐渐减少TNF抑制剂（TNFi）的随机对照试验中，试图进行渐缩的患者放射线照相进展最少。姿势

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《RMD Open》 |2017年第1期|共页
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Frank H J van den Hoogen; Robert B M Landewé; Noortje van Herwaarden; Alfons A den Broeder; Chantal A M Bouman; Aatke van der Maas;
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1. One-year maintenance with routine assessment of patient index data 3-based remission may inhibit radiographic progression in patients with rheumatoid arthritis treated with routine clinical therapy: A retrospective comparison of radiographic outcome and its prognostic factors between maintained remissions with patient-reported outcome index and physician-oriented disease activity indices (vol 26, pg 817, 2016) [J] . Katayama K., Okubo T., Sato T., Modern rheumatology . 2016,第5期

机译：通过常规评估患者指标数据进行为期一年的维护，基于常规3种缓解的类风湿性关节炎患者的放射学进展可能会抑制放射学进展：回顾性比较放射学结局及其预后因素与患者报告的结局指标和面向医师的疾病活动性指数（第26卷，第817页，2016年）
2. One-year maintenance with routine assessment of patient index data 3-based remission may inhibit radiographic progression in patients with rheumatoid arthritis treated with routine clinical therapy: A retrospective comparison of radiographic outcome and its prognostic factors between maintained remissions with patient-reported outcome index and physician-oriented disease activity indices [J] . Katayama Kou, Okubo Takanobu, Sato Toshikazu, Modern rheumatology . 2016,第6期

机译：通过常规评估患者指标数据进行为期一年的维护，基于常规3种缓解的类风湿性关节炎患者的放射学进展可能会抑制放射学进展：回顾性比较放射学结局及其预后因素与患者报告的结局指标和医师导向的疾病活动指数
3. Radiographic changes and factors associated with subsequent progression of damage in weight-bearing joints of patients with rheumatoid arthritis under TNF-blocking therapies-three-year observational study [J] . Matsushita Isao, Motomura Hiraku, Seki Eiko, Modern rheumatology . 2017,第4期

机译：TNF阻止治疗疗法下的类风湿性关节炎患者减肥关节损伤的后续进展相关的射线照相变化和因素
4. Development of TNF-alpha Inhibitor Drugs in Treatment of Rheumatoid Arthritis [C] . Dong Jin-rui, He Ming-hao, Han Mo, Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on . 2012

机译：TNF-α抑制剂在类风湿关节炎治疗中的应用
5. An increase in the frequency of hprt mutant T lymphocytes in the peripheral blood, synovial fluid, and synovial tissue of rheumatoid arthritis patients. [D] . Cannons, Jennifer. 1997

机译：类风湿性关节炎患者外周血，滑液和滑膜组织中hprt突变T淋巴细胞的频率增加。
6. Original article: What causes a small increase in radiographic progression in rheumatoid arthritis patients tapering TNF inhibitors? [O] . Chantal A M Bouman, Alfons A den Broeder, Aatke van der Maas, 2017

机译：原始文章：导致TNF抑制剂逐渐减少的类风湿关节炎患者的放射学进展略有增加的原因是什么？
7. What causes a small increase in radiographic progression in rheumatoid arthritis patients tapering TNF inhibitors? [O] . Bouman C.A.M., Broeder A.A. den, Maas A. van der, 2017

机译：是什么导致逐渐减少TNF抑制剂的类风湿关节炎患者的放射学进展略有增加？

What causes a small increase in radiographic progression in rheumatoid arthritis patients tapering TNF inhibitors?

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