Preparation and physicochemical and cytocompatibility analyses of a magnetic polymer colloid of xanthan gum-chitosanickel nanowires

摘要

A cross-linked polymer was formed by the reaction between chitosan (Cs) and xanthan gum (XG) at a weight ratio of 1:1. XG-Cs/Ni nanowire (XG-Cs/-Ni) was prepared by adding nickel nanowires (Ni, -Ni) into XG-Cs to form a nano-magnetic polymerization colloid. The results of SEM and TEM analysis showed that the diameter of the nickel nanowires is approximately 80?nm and the length is approximately 11?μm, with a high density and aspect ratio. The (1?1?1), (2?0?0), and (2?2?0) crystal planes were analyzed by XRD. The magnetic nanowires were measured on a vibrating sample magnetometer at 300?K. A perpendicular magnetic field was applied to the substrate, where coercivity was 685 Oe and the squareness was 0.866. An applied parallel magnetic field of the substrate revealed a coercivity (118 Oe) and a squareness (0.068). XG-Cs/-Ni was mixed, and its coercivity was determined to the range from 914 to 957 Oe. The melting points (59.0–197.3/695.5?°C) of XG-Cs/-Ni were measured by differential scanning calorimetry. Thermogravimetric analysis of XG-Cs/-Ni revealed three weight loss points. Furthermore, XG-Cs polymers support cell adhesion and proliferation of 3 tested cell lines, XG-Cs polymers show significant cytocompatibility.