首页> 外文期刊>Results in Physics >Multivariate analysis of trace elemental data obtained from blood serum of breast cancer patients using SRXRF
【24h】

Multivariate analysis of trace elemental data obtained from blood serum of breast cancer patients using SRXRF

机译:使用SRXRF对乳腺癌患者血清中的微量元素数据进行多变量分析

获取原文
       

摘要

Synchrotron radiation based X-ray fluorescence (SRXRF) technique was utilized for the determination of serum elemental profile in breast cancer patients group and healthy subjects group. The SRXRF experiments were performed on microprobe beamline-16, Indus-2 synchrotron radiation source at Raja Ramanna Centre for Advanced Technology (RRCAT), Indore, India. The accuracy and reliability of the experimental method were validated by using International Atomic Energy Agency (IAEA) reference material-animal blood (A-13). Sixteen elements were identified and their concentrations were measured in the serum of the two studied groups. The analysis of results showed significantly elevated levels of Fe (p?
机译:基于同步辐射的X射线荧光(SRXRF)技术用于确定乳腺癌患者组和健康受试者组的血清元素谱。 SRXRF实验是在印度印多尔Raja Ramanna先进技术中心(RRCAT)的Indus-2同步加速器微探针束线16上进行的。实验方法的准确性和可靠性通过使用国际原子能机构(IAEA)参考材料-动物血液(A-13)进行了验证。在两个研究组的血清中鉴定出16种元素,并测量了它们的浓度。结果分析表明,Fe(p 0.000005),Cu(p 0.000001)和Pb(p 0.00001)和Fe(p 0.0005),Cr( p <0.05,Mn(p <0.000005),Co(p <0.001),Zn(p <0.000005),Se(p <0.000005)和Br(p <0.05)。 )相对于健康受试者的乳腺癌患者血清中的)。对获得的数据进行相关性分析,发现两个研究组中某些元素的相关性模式显着不同。借助判别分析,可以确定两个研究组之间血清元素谱的差异,总准确性为98.8%。预期受某些痕量元素浓度变化的影响的病理机制可能导致了致癌过程。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号