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UPDATING ON DIAGNOSIS AND TREATMENT OF CHONDRAL LESION OF THE KNEE

机译:更新膝关节软骨病变的诊断和治疗

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ABSTRACTS The treatment of chondral knee injuries remains a challenge for the orthopedic surgeon, mainly owing to the characteristics of the cartilage tissue, which promote low potential for regeneration. Chondral lesions can be caused by metabolic stimulation, or by genetic, vascular and traumatic events, and are classified according to the size and thickness of the affected cartilage. Clinical diagnosis can be difficult, especially due to insidious symptoms. Additional tests, as Magnetic Resonance Imaging (MRI), may be needed. The treatment of these lesions usually starts with non-operative management. Surgery should be reserved for patients with detached chondral fragments, blocked range of motion, or the failure of non-operative treatment. The surgical techniques used for the treatment of partial thickness defects are Debridement and Ablation. These techniques aim to improve symptoms, since they do not restore normal structure and function of the cartilage. For full-thickness defects (osteochondral lesion), available treatments are Abrasion, Drilling, Microfracture, Osteochondral Autologous and Allogeneic Transplantation, and biological techniques such as the use of Autologous Chondrocyte Transplantation, Minced Cartilage and stem cells.
机译:摘要软骨膝关节损伤的治疗仍然是整形外科医生所面临的挑战,这主要归因于软骨组织的特征,这些特征促进了低的再生潜力。软骨损伤可以由代谢刺激或遗传,血管和创伤事件引起,并根据患软骨的大小和厚度进行分类。临床诊断可能很困难,尤其是由于阴险的症状。可能需要进行其他检查,例如磁共振成像(MRI)。这些病变的治疗通常始于非手术治疗。软骨碎片脱落,活动范围受阻或非手术治疗失败的患者应保留手术。用于治疗局部厚度缺损的外科技术是清创术和消融术。这些技术旨在改善症状,因为它们不能恢复软骨的正常结构和功能。对于全层缺损(软骨软骨病变),可用的治疗方法包括磨蚀,钻孔,微骨折,骨软骨自体和同种异体移植,以及生物技术,例如使用自体软骨细胞移植,软骨和干细胞移植。

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