Perda auditiva associada à exposi??o ocupacional a solventes organicos: uma revis?o sistemática

摘要

MONT'ALVERNE, Lucienne Rezende; CORONA, Ana Paula ?and? REGO, Marco Ant?nio Vasconcelos. Hearing loss associated with organic solvent exposure: a systematic review. Rev. bras. saúde ocup. [online]. 2016, vol.41, e10. ?Epub?Oct?10, 2016. ISSN 0303-7657.? http://dx.doi.org/10.1590/2317-6369000113615. Introduction: evidences indicate chemicals as potentially otoneurotoxic agents; however, there is no consensus as to the associations between exposure characteristics and the ototoxicity of different chemicals present in industrial environments. Objective: to review the available scientific literature in order to identify studies that point to evidence of association, or non-association, between hearing impairment and occupational exposure to organic solvents. Method: systematic review of the literature, through query on electronic databases, considering only original articles, published from January 1987 to February 2013. Results: thirty-one studies were included in the systematic review. Discussion: studies have confirmed exposure to certain solvents as a risk factor for occupational hearing loss, especially in the presence of noise. Various assessment and classification methods were used regarding cochlear and/or central hearing impairment, contributing to the understanding of the extent of chemical-induced hearing loss as well as to the identification of populations at risk. However, data on appropriate diagnostic procedures, safe levels of chemical exposure and dose-response effect have not yet been fully elucidated.