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Management of Vesicoureteral Reflux by Endoscopic Injection of Dextranomer/Hyaluronic Acid in Adults

机译:成人内镜下右旋糖酐/透明质酸注射治疗输尿管反流

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A 74-year-old man presented for evaluation after discovery of a left bladder-wall tumor. He underwent transurethral resection of bladder tumor (TURBT) operation for treatment of low-grade, Ta urothelial cancer of the bladder. The patient developed recurrent disease and returned to the operating room for repeat TURBT, circumcision, and administration of intravesical mitomycin C. The patient developed balanitis xerotica obliterans 4 years post-circumcision, requiring self-dilation with a catheter. He subsequently developed 3 consecutive episodes of left-sided pyelonephritis. Further investigation with voiding cystourethrogram (VCUG) revealed Grade 3, left-sided vesicoureteral reflux (VUR). Due to existing comorbidities, the patient elected treatment with endoscopic dextranomer/hyaluronic acid injection. A post-operative VCUG demonstrated complete resolution of left-sided VUR. This patient has remained symptom free for 8 months post-injection, with no episodes of pyelonephritis.
机译:在发现左膀胱壁肿瘤后,一名74岁男子提出进行评估。他接受了经尿道膀胱肿瘤切除术(TURBT)的手术,以治疗低度的膀胱尿路上皮癌。患者发展为复发性疾病,并返回手术室重复进行TURBT,包皮环切术和膀胱内丝裂霉素C给药。包皮环切术后4年,患者患上了干性龟头炎,需要用导管自行扩张。随后,他连续3次发作左侧肾盂肾炎。进一步的尿道膀胱尿道造影(VCUG)检查显示为3级,左侧膀胱输尿管反流(VUR)。由于存在合并症,患者选择了内窥镜右旋糖酐/透明质酸注射液治疗。术后VCUG证实左侧VUR完全消退。该患者注射后8个月无症状,无肾盂肾炎发作。

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