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Two years experience with quality assurance protocol for patient related Rapid Arc treatment plan verification using a two dimensional ionization chamber array

机译:使用二维电离室阵列进行与患者相关的快速电弧治疗计划验证的质量保证协议的两年经验

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Purpose To verify the dose distribution and number of monitor units (MU) for dynamic treatment techniques like volumetric modulated single arc radiation therapy - Rapid Arc - each patient treatment plan has to be verified prior to the first treatment. The purpose of this study was to develop a patient related treatment plan verification protocol using a two dimensional ionization chamber array (MatriXX, IBA, Schwarzenbruck, Germany). Method Measurements were done to determine the dependence between response of 2D ionization chamber array, beam direction, and field size. Also the reproducibility of the measurements was checked. For the patient related verifications the original patient Rapid Arc treatment plan was projected on CT dataset of the MatriXX and the dose distribution was calculated. After irradiation of the Rapid Arc verification plans measured and calculated 2D dose distributions were compared using the gamma evaluation method implemented in the measuring software OmniPro (version 1.5, IBA, Schwarzenbruck, Germany). Results The dependence between response of 2D ionization chamber array, field size and beam direction has shown a passing rate of 99% for field sizes between 7 cm × 7 cm and 24 cm × 24 cm for measurements of single arc. For smaller and larger field sizes than 7 cm × 7 cm and 24 cm × 24 cm the passing rate was less than 99%. The reproducibility was within a passing rate of 99% and 100%. The accuracy of the whole process including the uncertainty of the measuring system, treatment planning system, linear accelerator and isocentric laser system in the treatment room was acceptable for treatment plan verification using gamma criteria of 3% and 3 mm, 2D global gamma index. Conclusion It was possible to verify the 2D dose distribution and MU of Rapid Arc treatment plans using the MatriXX. The use of the MatriXX for Rapid Arc treatment plan verification in clinical routine is reasonable. The passing rate should be 99% than the verification protocol is able to detect clinically significant errors.
机译:目的为了验证动态治疗技术(例如体积调制单弧放射治疗-快速电弧治疗)的剂量分布和监护单元(MU)的数量,必须在首次治疗之前验证每个患者的治疗计划。这项研究的目的是使用二维电离室阵列(MatriXX,IBA,Schwarzenbruck,德国)制定与患者相关的治疗计划验证方案。方法进行测量以确定2D电离室阵列的响应,束方向和场大小之间的依赖性。还检查了测量的可重复性。为了进行患者相关验证,将原始患者Rapid Arc治疗计划投影到MatriXX的CT数据集上,并计算出剂量分布。辐照Rapid Arc验证计划后,使用在测量软件OmniPro(1.5版,IBA,Schwarzenbruck,德国)中实施的伽马评估方法,比较测量和计算的2D剂量分布。结果二维电离室阵列的响应,场大小和射束方向之间的相关性表明,对于单弧测量,在7 cm×7 cm和24 cm×24 cm之间的场大小下,通过率为99%。对于小于和等于7 cm×7 cm和24 cm×24 cm的更大尺寸的场,通过率小于99%。重现性在99%和100%的合格率范围内。使用3%和3 mm的伽玛标准,二维全局伽玛指数进行的治疗计划验证,包括测量系统,治疗计划系统,线性加速器和等中心激光系统的不确定性在内的整个过程的准确性对于治疗计划是可以接受的。结论使用MatriXX可以验证快速电弧治疗计划的2D剂量分布和MU。在临床常规中使用MatriXX进行快速电弧治疗计划验证是合理的。通过率应为验证协议能够检测出临床上显着错误的99%。

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