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首页> 外文期刊>Revista Brasileira de Anestesiologia >Papel da lidocaína por via venosa no tratamento da dor na esclerodermia: relato de caso
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Papel da lidocaína por via venosa no tratamento da dor na esclerodermia: relato de caso

机译:未经治疗的静脉注射利多卡因在硬皮病中的作用:病例报告

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BACKGROUND AND OBJECTIVES: Scleroderma or progressive systemic sclerosis is a systemic connective tissue disease of unknown origin, which normally courses with microangiopathy, extremities ischemia and severe pain. This report aimed at describing a case of intravenous lidocaine to treat ischemic pain and at emphasizing potential anti-inflammatory action of local anesthetics in scleroderma patients. CASE REPORT: Female patient, clear mulatto 34 years old, nursing assistant, with scleroderma for approximately 8 years, presented with severe continuous, daily pain (numeric scale = 10) in upper and lower limbs, followed by trophic, color and temperature changes, and small ulcers on extremities. Patient was submitted to 1 weekly session of intravenous 2% lidocaine (400 mg) without vasoconstrictor for 10 weeks with pain, turgor, skin elasticity and peripheral perfusion improvement. CONCLUSIONS: Pain and other symptoms relief after intravenous lidocaine suggests that local anesthetics are able to modulate inflammatory response in different scleroderma stages.
机译:背景与目的:硬皮病或进行性系统性硬化症是一种来源不明的全身性结缔组织疾病,通常伴有微血管病变,四肢缺血和严重疼痛。该报告旨在描述一例静脉注射利多卡因治疗局部缺血性疼痛并强调硬皮病患者局部麻醉药潜在的抗炎作用。病例报告:女性患者,34岁的纯正黑白混血儿,护理助理,患有硬皮病约8年,在上肢和下肢出现严重的连续日常疼痛(数字等级= 10),随后出现营养,颜色和温度变化,和四肢小溃疡。患者每周接受1次无血管收缩剂的2%利多卡因静脉注射(400毫克),持续10周,可缓解疼痛,肿胀,皮肤弹性和周围灌注。结论:静脉注射利多卡因后疼痛和其他症状缓解,表明局部麻醉药能够调节不同硬皮病阶段的炎症反应。

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