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If something looks like an apple, is it necessarily an apple? Some considerations about so-called “statin-induced polymyalgia rheumatica”

机译:如果某物看起来像苹果,那一定是苹果吗?关于所谓的“他汀类药物引起的风湿性多肌痛”的一些考虑

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The existence of polymyalgia rheumatica (PMR) induced by statins has been hypothesised by some investigators. This review article highlights the fact that there is no evidence it is real. On the contrary, PMR and statin-associated muscle symptoms (SAMS) are two totally different conditions. Shoulder and hip ultrasound (US) examinations can make an important contribution in distinguishing a?true case of PMR from a?PMR-like illness induced by statins. The possibility that SAMS may worsen the clinical manifestations of a?PMR patient should be taken into account in clinical practice, and drug discontinuation should be proposed when deterioration or relapse is not otherwise justifiable.
机译:他汀类药物引起的风湿性多肌痛(PMR)的存在已被一些研究者假设。这篇评论文章强调了没有证据是真实的事实。相反,PMR和他汀类药物相关的肌肉症状(SAMS)是两种完全不同的疾病。肩部和髋部超声检查(US)可为将PMR的真实病例与他汀类药物引起的PMR样疾病区分开来做出重要贡献。在临床实践中应考虑SAMS可能使a?PMR患者的临床表现恶化的可能性,并且在没有其他理由证明恶化或复发的情况下应建议停药。

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