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Multiparametric MR imaging in diagnosis of chronic prostatitis and its differentiation from prostate cancer

机译:多参数磁共振成像对慢性前列腺炎的诊断及其与前列腺癌的鉴别

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摘要

Chronic prostatitis is a heterogeneous condition with high prevalence rate. Chronic prostatitis has overlap in clinical presentation with other prostate disorders and is one of the causes of high serum prostate specific antigen (PSA) level. Chronic prostatitis, unlike acute prostatitis, is difficult to diagnose reliably and accurately on the clinical grounds alone. Not only this, it is also challenging to differentiate chronic prostatitis from prostate cancer with imaging modalities like TRUS and conventional MR Imaging, as the findings can mimic those of prostate cancer. Even biopsy doesn't play promising role in the diagnosis of chronic prostatitis as it has limited sensitivity and specificity. As a result of this, chronic prostatitis may be misdiagnosed as a malignant condition and end up in aggressive surgical management resulting in increased morbidity. This warrants the need of reliable diagnostic tool which has ability not only to diagnose it reliably but also to differentiate it from the prostate cancer. Recently, it is suggested that multiparametric MR Imaging of the prostate could improve the diagnostic accuracy of the prostate cancer. This review is based on the critically published literature and aims to provide an overview of multiparamateric MRI techniques in the diagnosis of chronic prostatitis and its differentiation from prostate cancer.
机译:慢性前列腺炎是一种异质性疾病,患病率很高。慢性前列腺炎在临床表现上与其他前列腺疾病重叠,并且是血清前列腺特异性抗原(PSA)水平高的原因之一。与急性前列腺炎不同,慢性前列腺炎仅凭临床原因就难以可靠,准确地诊断。不仅如此,通过像TRUS和常规MR成像这样的成像方式将慢性前列腺炎与前列腺癌区分开来也是一项挑战,因为这些发现可以模仿前列腺癌。甚至活检在慢性前列腺炎的诊断中也没有发挥有希望的作用,因为它的敏感性和特异性有限。结果,慢性前列腺炎可能被误诊为恶性疾病,最终导致积极的外科治疗,导致发病率增加。这保证了需要可靠的诊断工具,该工具不仅具有可靠地诊断能力,而且具有将其与前列腺癌区分开的能力。最近,建议对前列腺进行多参数MR成像可以提高前列腺癌的诊断准确性。这篇综述基于重要发表的文献,旨在概述多参数MRI技术在慢性前列腺炎及其与前列腺癌的鉴别诊断中的作用。

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