Study of Antioxidant Activity of Datura stramonium Linn.

摘要

The present study aims to investigate the m ethanolic extract of different plant parts of, Datura stramonium Linn (family Solanaceae) for their antioxidant activity . The maximum DPPH scavenging activity of extract and standard was found to be 92.3% at 1000 μg mL^-1 and 92.8% at 1000 and 512 μg mL^-1, respectively. The IC₅₀ of the M ethanolic extract of Datura stramonium and standard was found to be 39.48 and 42.0 μg mL^-1, respectively. The maximum superoxide scavenging activity of plant extract and standard was found to be 73.1 and 83.4% at 128 μg mL^-1. The IC₅₀ value of plant extract and standard was found to be 28.45 and 42.32 μg mL^-1, respectively. Maximum chelating of metals ions at 1000 μg mL^-1 of extract and standard was found to be 63.9 and 89%, respectively. The IC₅₀ values of plant extract and standard was recorded as 26.45 and 58.41 μg mL^-1, respectively. The maximum ABTS scavenging activity of plant extract and standard was found to be 84.5 and 79.2% at 256 and 128 μg mL^-1, respectively. The IC₅₀ value of plant extract and standard was recorded as 40.11 and 24.29 μg mL^-1, respectively. The maximum nitric oxide radical scavenging activity of extract and standard was found to be 63.1 and 72.3% at 1000 and 512 μg mL^-1, respectively. The IC₅₀ value of the methanol extract and standard was found to be 35.85 and 29.34 μg mL^-1, respectively.