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gset: An R Package for Exact Sequential Test of Equivalence Hypothesis Based on Bivariate Non-Central t-Statistics

机译:gset:基于二元非中心t统计量的等价假设的精确顺序检验的R包

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摘要

The R package gset calculates equivalence and futility boundaries based on the exact bivariate non-central t test statistics. It is the first R package that targets specifically at the group sequential test of equivalence hypotheses. The exact test approach adopted by gset neither assumes the large-sample normality of the test statistics nor ignores the contribution to the overall Type I error rate from rejecting one out of the two one-sided hypotheses under a null value. The features of gset include: error spending functions, computation of equivalence boundaries and futility boundaries, either binding or nonbinding, depiction of stagewise boundary plots, and operating characteristics of a given group sequential design including empirical Type I error rate, empirical power, expected sample size, and probability of stopping at an interim look due to equivalence or futility.
机译:R包gset基于确切的双变量非中心t检验统计量计算等效和无效边界。它是第一个专门针对等效假设的小组顺序检验的R软件包。 gset所采用的精确测试方法既不假设测试统计信息具有大样本正态性,也不能忽略在无效值下拒绝两个单方面假设中的一个而对总体I型错误率的影响。 gset的功能包括:错误支出函数,等效边界和无效边界的计算(有约束力或无约束力),阶段边界图的描述以及给定组顺序设计的操作特征,包括经验I型错误率,经验功效,预期样本大小,以及由于等价或徒劳而停在临时外观上的可能性。

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