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Clinical evaluation following the use of mineralized collagen graft for bone defects in revision total hip arthroplasty

机译:使用矿化胶原蛋白移植物治疗翻修全髋关节置换术中骨缺损的临床评估

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Revision total hip arthroplasty (THA) with massive bone loss has been a real challenge for orthopaedic surgeons. Here we describe an approach using mineralized collagen (MC) graft to reconstruct acetabulum and femur with massive bone defects. We identified 89 patients suffering acetabular or femoral bone defects after primary THA, who required revision THA for this study. During the surgery, MC was applied to reconstruct both the acetabular and femoral defects. Harris hip score was used to evaluate hip function while radiographs were taken to estimate bone formation in the defect regions. The average follow-up period was 33.6?±?2.4 months. None of the components needed re-revised. Mean Harris hip scores were 42.5?±?3.5 before operation, 75.2?±?4.0 at 10th month and 95.0?±?3.6 at the final follow-up. There were no instances of deep infection, severe venous thrombosis or nerve palsy. The present study demonstrated that MC graft can serve as a promising option for revision THA with massive bone deficiency. Meanwhile, extended follow-up is needed to further prove its long-term performance.
机译:对整形外科医师来说,伴有大量骨丢失的全髋关节置换术(THA)的修复一直是一个真正的挑战。在这里,我们描述了一种使用矿化胶原蛋白(MC)移植物重建具有大量骨缺损的髋臼和股骨的方法。我们确定了89例原发性THA后患有髋臼或股骨缺损的患者,该患者需要本研究进行THA修订。在手术过程中,MC被用于重建髋臼和股骨缺损。使用Harris髋关节评分来评估髋关节功能,同时使用X线照片评估缺损区域的骨形成。平均随访时间为33.6±2.4个月。没有任何组件需要重新修订。 Harris的平均术前评分为42.5±3.5,在术后10个月为75.2±4.0,最后一次随访为95.0±3.6。没有发生深度感染,严重静脉血栓形成或神经麻痹的情况。本研究表明,MC移植物可作为严重骨缺损的THA翻修术的有希望的选择。同时,需要进一步跟踪以进一步证明其长期性能。

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