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Diets containing traditional and novel green leafy vegetables improve liver fatty acid profiles of spontaneously hypertensive rats

机译:含有传统和新型绿叶蔬菜的饮食可改善自发性高血压大鼠的肝脏脂肪酸谱

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Background The consumption of green leafy vegetables (GLVs) has been demonstrated to reduce the risks associated with cardiovascular and other diseases. However, no literature exists that examines the influence of traditional and novel GLVs on the liver fatty acid profile of an animal model genetically predisposed to developing hypertension. The aim of the present study was to examine the effects of diets containing 4% collard greens, purslane or sweet potato greens on the liver fatty acid profiles of four-week old male spontaneously hypertensive rats (SHRs, N?=?44). Following four weeks consumption of the diets, liver fatty acid profiles were determined by gas–liquid chromatography of transesterified fatty acid methyl esters. Results SHRs consuming the control diet had greater percentages of liver saturated fatty acid and less omega-3 fatty acid percentages. SHRs consuming the diets containing vegetables had significantly greater liver concentrations of γ- linolenic, docosahexaenoic and docosahexaenoic acids, as well as lower levels of lauric, palmitic and arachidonic acids. SHRs consuming the control diet had significantly greater percentages (p?
机译:背景技术已证明食用绿叶蔬菜(GLV)可以减少与心血管疾病和其他疾病相关的风险。然而,没有文献检查传统的和新型的GLV对遗传上倾向于发展为高血压的动物模型的肝脏脂肪酸谱的影响。本研究的目的是检验含4%羽衣甘蓝,马齿sl或甘薯的饮食对四周大的雄性自发性高血压大鼠(SHRs,N≥44)的肝脏脂肪酸谱的影响。进食四周后,通过酯交换脂肪酸甲酯的气相色谱法测定肝脏脂肪酸谱。结果食用对照饮食的SHRs的肝脏饱和脂肪酸百分比更高,而omega-3脂肪酸百分比更低。食用含有蔬菜的饮食的SHR肝脏中的γ-亚麻酸,二十二碳六烯酸和二十二碳六烯酸的浓度显着较高,而月桂酸,棕榈酸和花生四烯酸的含量较低。食用对照饮食的SHRs的油酸百分比显着更高(p <0.05)。明显少于γ-亚麻酸和二十二碳六烯酸结论这项研究证明了GLV调节肝脏脂肪酸组成的能力,从而提供了针对动脉粥样硬化脂肪酸升高的保护作用,而后者可能与CVD的发病机制有关。因此,预防CVD的饮食建议应考虑可能的心脏保护作用,以及含羽衣甘蓝,马齿sl和甘薯的饮食所带来的脂肪酸分布的后续改变。

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