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The role of functional foods in the psychobiology of health and disease

机译:功能性食品在健康与疾病心理生物学中的作用

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AbstractThe effect of psychological stress on health is becoming a serious concern, with figures from the World Health Organization showing that stress-related disorders affect nearly 450 million individuals worldwide. Heightened physiological stress responses and psychosocial factors have been linked to disease pathways such as hypertension and CVD. This has prompted significant interest within the scientific community, public health bodies and industry to employ interventions to control and reduce the impact of stress on health. There is now strong potential for functional foods to offer stress management benefits. Various physiological pathways have been targeted by specific dietary supplements for stress reduction, including the hypothalamica€“pituitarya€“adrenal axis and sympathetic nervous system. Presently there are a number of ingredients, which include vitamin C, milk proteins, a number of herbal extracts (ginkgo biloba, ginseng, kava, valerian and lemon balm), and n-3 fatty acids, that have demonstrated potential stress reactivity-lowering and mood-enhancing effects, although further work is required to substantiate the efficacy in human subjects. Dietary supplements that can alleviate excessive stress responses may play an increasingly important role for the maintenance of health in a stressful environment. However, future research should employ a greater range of measures that will provide stronger evidence to substantiate functional food claims for stress relief.
机译:摘要世界卫生组织(WHO)的数据显示,心理压力对健康的影响正成为一个严重的问题,全世界与压力有关的疾病影响了近4.5亿人。较高的生理应激反应和社会心理因素已与诸如高血压和CVD的疾病途径相关。这引起了科学界,公共卫生机构和行业的极大兴趣,他们采取干预措施来控制和减少压力对健康的影响。现在,功能性食品具有很大的潜力来提供压力管理的好处。特定的饮食补充剂已针对减少应激的各种生理途径,包括下丘脑,“垂体”,肾上腺轴和交感神经系统。目前有许多成分,包括维生素C,牛奶蛋白,多种草药提取物(银杏,人参,卡瓦,缬草和柠檬香脂)以及n-3脂肪酸,它们均具有降低潜在的应激反应性的作用。增强情绪的作用,尽管还需要进一步的工作来证实其在人类受试者中的功效。可以减轻过度压力反应的膳食补充剂在维持压力环境中的健康方面可能发挥越来越重要的作用。但是,未来的研究应采用更多的措施,以提供有力的证据来证实功能性食品可以缓解压力。

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