Abstract：Objective To compare the nasal damage in premature infant with apnea undergoing oxygen inhalation therapy by humidified high flow nasal cannula (HHFNC) and nasal continuous positive airway pressure (NCPAP). Methods A total of 65 premature infants diagnosed as apnea were randomly divided into HHFNC group(n=33) and NCPAP group(n=32). The ventilatory support based on 3M transparent dressings nasal protection and conventional nursing care were given in HHFNC and NCPAP. The nasal damage was evaluated and compared between two groups. Results The nasal damage score referring to right side, the left side and nasal septum in group NCPAP was higher than those in HHFNC group (P＜0.05 or P＜0.01). There was no significant difference in damage score of nasal middle part between two groups (P＞0.05). Conclusion Appling HHFNC may lead less nasal damage in treatment of premature infant with apnea.
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