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首页> 外文期刊>Kidney International Reports >Strongyloides stercoralis?Associated Tip Variant Focal Segmental Glomerulosclerosis
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Strongyloides stercoralis?Associated Tip Variant Focal Segmental Glomerulosclerosis

机译:硬脂酸类固醇?相关的尖端变异性局灶性节段性肾小球硬化症

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Approximately 100 million people worldwide are infected with the intestinal nematode Strongyloides stercoralis (StrS). This roundworm is endemic intropical and subtropical regions.1–4 StrS has an autoinfective cycle that allows it to survive and replicate ina human host for many years.4 StrS has 2 important lifestages, namely, filarial and rhabditiform. In the filarialstage, StrS enters its human host percutaneouslythrough feces-contaminated soil. In the rhabditiformstage, StrS lays eggs that hatch into larvae in the duodenum and are passed into the stool. Most patientswith StrS infection remain asymptomatic. Althoughparasitic infections are known to be associated withimmune complexmediated glomerular lesions, StrSassociated glomerulopathy has not been welldocumented.
机译:全世界大约有1亿人感染了肠道线虫stercoralis(StrS)。这种round虫是地方性的热带和亚热带地区。1–4 StrS具有自感染周期,可以使其在人类宿主中存活并复制多年。4StrS具有2个重要的生命周期,即丝状和横纹状。在丝虫期,StrS通过粪便污染的土壤经皮进入人类宿主。在大黄形阶段,StrS产卵,将卵孵化到十二指肠的幼虫中并传递到粪便中。大多数患有StrS感染的患者仍无症状。尽管已知寄生虫感染与免疫复合物介导的肾小球病变有关,但是StrS相关性肾小球病尚未得到充分的证明。

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