SUN-081 THE EFFECT OF ASTRAGALOSIDE-IV ON OXYGEN STRESS AND EMT OF HMRSV5 INDUCED BY HIGH-GLUCOSE PERITONEAL DIALYSATE

摘要

In the largest international cohort of PD patients to date, we have demonstrated significant variations in peritonitis incidence and outcomes by country. In Thailand, a PD-first country with more limited resources, peritonitis incidence was comparable to other countries. However, a higher culture-negative peritonitis rate and significantly higher peritonitis-related adverse outcomes in Thailand compared to other countries (higher death, lower cure) suggest op- portunities to improve peritonitis diagnosis and treatment. As a clinical practice, exit-site antimicrobial prophylaxis remains a mainstay of peritonitis prevention. Further investigation into the optimal exit site antimicrobial agent will be explored in PDOPPS along with other peritonitis prevention strategies.