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Never Ending Challenge of Dengue - Current Scenario in the Hilly State of North India

机译:登革热永无止境的挑战-印度北部丘陵州的当前情景

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Introduction: Dengue is an arthropod borne (Arbovirus) viral infection. It is the most common arthropod borne virus found in India. It is transmitted principally by vector Aedes aegypti followed by Aedes albopictus. Due to cold weather Dengue is not endemic in Himachal Pradesh, however the number of cases are now on an increase. Also, there is paucity of published studies from this state on dengue.Aim: To estimate the current scenario of Dengue in this hilly state of North India in patients visiting our hospital. We also compared two tests i.e. NS1 antigen capture ELISA test and Dengue IgM Capture ELISA test for diagnosis of dengue.Materials and Methods: All cases with fever and suspected dengue infection were included in the study. Total 225 blood samples were collected from these patients. NS1 antigen and IgM detection were performed for diagnosis.Results: Out of total 225 suspected cases 73 cases (32.4%) were diagnosed with dengue infection. Overall NS 1 antigen ELISA was a more sensitive test as compared to IgM capture ELISA.Conclusion: Rapid tests must be performed early in thecourse of disease to establish diagnosis and initiate symptomatic treatment. Multiple tests done together enhance chances of dengue detection and are recommended. Vector control is the main key to control dengue spread in future.
机译:简介:登革热是一种节肢动物传播的(虫媒病毒)病毒感染。它是印度发现的最常见的节肢动物传播的病毒。它主要由媒介埃及伊蚊传播,然后由白纹伊蚊传播。由于寒冷的天气,登革热在喜马al尔邦不是地方性流行,但是现在病例数正在增加。此外,该州有关登革热的研究也很少。目的:评估北印度这个丘陵州的登革热目前就诊情况。我们还比较了两种检测方法,即NS1抗原捕获ELISA检测和登革热IgM捕获ELISA检测对登革热的诊断。材料与方法:本研究包括所有发烧和疑似登革热感染的病例。从这些患者中收集了总共225份血液样本。结果:在225例疑似病例中,有73例(32.4%)被诊断为登革热感染。与IgM捕获ELISA相比,总的NS 1抗原ELISA检测更为敏感。结论:必须在疾病早期及早进行快速检测,以建立诊断和对症治疗。建议同时进行多项测试,以增加登革热检测的机会。矢量控制是将来控制登革热传播的主要关键。

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