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A Morphologic Study of Cutaneous Adnexal Tumours

机译:皮肤肾上腺肿瘤的形态学研究

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Introduction: Cutaneous adnexal tumour is a collective term for tumours arising from various adnexal units of the skin. These tumours share many common features even though they differentiate along one line. They can only be categorized on microscopic examination and not by clinical manifestations. Their microscopic classification also is difficult owing to the variety of tissue elements, patterns and metaplastic transformations in these tumours.Aim: To review and classify all dermal adnexal tumors diagnosed in the Pathology Department of SMVMCH over the period of 6 years spanning from January 2007 to December 2012, and also to differentiate dermal adnexal tumours from other cutaneous tumours by pattern recognition (morphological identification of varied histopathological features).Materials and Methods: All adnexal tumors diagnosed in the Pathology Department of Sri Manakula Vinayagar Medical College and Hospital (SMVMCH) over the period of 6 years was studied. The Hematoxylin and Eosin stained slides were analyzed for patterns to differentiate each entity from other cutaneous tumours.Results: Twenty adnexal tumors were diagnosed over a period of 6 years. Clinical presentations varied from discrete swellings and nodules to ulcerated masses. Most of the lesions were distributed in the head, neck and extremities. Histologically 17 cases were benign and 3 tumours were malignant. Commonest tumour encountered was eccrine acrospiroma followed by pilomatricoma and syringoma. Malignant tumours encountered were eccrine porocarcinoma, malignant eccrine spiradenoma and malignant adnexal tumour.Conclusion: Cutaneous adnexal tumours are complex due to their diverse origin and varied histological appearance. Many of these entities have morphological overlap. Although majorities of adnexal tumours are benign, malignant counterparts are also rarely encountered, causing further diagnostic difficulties. By far the commonest variant in the present study was of eccrine sweat gland origin.
机译:简介:皮肤附件肿瘤是由皮肤各个附件单元引起的肿瘤的统称。这些肿瘤即使沿一条线分化也具有许多共同特征。它们只能在显微镜检查下分类,而不能通过临床表现分类。由于这些肿瘤的组织成分,模式和化生转化的多样性,它们的显微镜分类也很困难。目的:回顾和分类从2007年1月至2007年6月期间在SMVMCH病理科诊断出的所有真皮附件肿瘤。 2012年12月,也通过模式识别(各种组织病理学特征的形态学鉴定)将真皮附件肿瘤与其他皮肤肿瘤区分开。材料与方法:在斯里兰卡玛纳库拉·维纳雅加尔医学院和医院(SMVMCH)病理科诊断的所有附件肿瘤研究了6年的时间。对苏木精和曙红染色的载玻片进行分析,以区分每个实体与其他皮肤肿瘤。结果:在6年的时间里,诊断出20例附件性肿瘤。临床表现从离散的肿胀和结节到溃疡的肿块不等。大多数病变分布在头部,颈部和四肢。组织学上为良性17例,恶性3例。遇到的最常见的肿瘤是外分泌性顶螺旋体瘤,其次是pilomatricoma和syringoma。遇到的恶性肿瘤包括内分泌性腺癌,恶性内分泌螺旋体瘤和恶性附件瘤。结论:皮肤附件肿瘤由于来源多样,组织学形态多样而复杂。这些实体中许多都具有形态重叠。尽管大多数附件肿瘤是良性的,但也很少遇到恶性对应物,从而导致进一步的诊断困难。到目前为止,本研究中最常见的变异是内分泌汗腺来源。

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