Gout is caused by persistent chronic hyperuricemia and is characterized clinically by relapsing and remitting attacks of joint pain. The deposition of monosodium urate crystals in and around joints, skin and soft tissue produces masses commonly referred to as tophi. Rare cases can present initially as tophaceous gout without features of arthritis. Below we report 2 cases clinically suspicious of neoplastic process; where cytology was diagnostic of gouty tophi. One of our cases presented as lytic lesion of bone without features of arthritis. The use of fine needle aspiration (FNA) cytology in periarticular and soft tissue nodules is highlighted.
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