The importance of bisphenol A, an uraemic toxin from exogenous sources, in haemodialysis patients

摘要

In recent years in the scientific community, the harmful effect of a phenolic type of environmental toxicant, known as bisphenol A (BPA), has achieved great relevance (Fig. 1). The interest in this compound is increasing owing to its possible adverse effects on several organs, which has led several organisations to recommend the prohibition or at least use reduction, with wide repercussions in the media. BPA has also aroused interest in the nephrological community, as it has been linked to kidney and endocrine disorders. Since BPA is cleared by the kidneys, plasma and tissue levels of BPA are markedly increased in patients with impaired renal function.