Uremic cardiomyopathy and peritoneal transport in incident peritoneal dialysis patients in the west of Mexico

摘要

In Mexico as in the rest of the world there is an increase in the frequency of chronic kidney disease (CKD) that progresses to end stage renal disease (CKD5D) and requires renal replacement therapy such as peritoneal dialysis (PD).1,2 In CKD5D morbidity and mortality are mainly due to cardiovascular disease (CVD).3,4 Uremic cardiomyopathy (UCM) results from abnormalities in cardiac structure and function in patients with CKD3-5. UCM predicts mortality due to the presence of cardiac abnormalities present at the onset of PD4,5 and are characterized by left ventricular hypertrophy (LVH), left ventricular dilatation and both systolic and diastolic heart dysfunction.5 Echocardiography detects abnormalities related to UCM3,4,6 that impact the prognosis of CKD5D patients initiating PD.6 The peritoneal equilibration test (PET)7 evaluates the function of the peritoneal membrane and allows to classify patients as different types of transporters and has a prognostic value.8,9 The aim of the study was to describe echocardiographic findings related to UCM at the commencement of CAPD; these findings were correlated with the type of peritoneal transport (PT).