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Three new nortriterpenoids from Schisandra wilsoniana and their anti-HIV-1 activities

机译:北五味子的三种新降冰片萜及其抗HIV-1活性

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Three new highly oxygenated nortriterpenoids, wilsonianadilactones D–F (1–3), were isolated from the leaves and stems of Schisandra wilsoniana. Their structures were established by means of spectroscopic analysis. Compounds 1–3 showed weak anti-HIV-1 activity with the therapeutic index (TI) values (CC50/EC50) greater than 8.16, 14.7, and 17.5, respectively.
机译:从北五味子的叶子和茎中分离出三种新的高含氧量的降水三萜类化合物,wilsonianadilactones D–F(1-3)。通过光谱分析确定它们的结构。化合物1-3显示弱的抗HIV-1活性,治疗指数(TI)值(CC50 / EC50)分别大于8.16、14.7和17.5。

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