Use HFR-supra for porphyria cutanea tarda treatment in hemodialysis patient

摘要

We present the case of a 53-year-old man on long-term hemodialysis since July 2008 secondary to diabetic nephropa- thy. His previous medical history included type 2 diabetes with poor metabolic control, morbid obesity, hypertension (HTN), severe mixed dyslipidaemia, secondary hyperparathyroidism, hyperuricaemia and Child-Pugh B7 chronic alcoholic liver dis- ease. In August 2016, he developed erosive, vesicular, painful esions on his upper limbs, abdomen and lower limbs which became worse when exposed to the sun. Tests for faecal proto- porphyrins were positive (53 .g/g) and skin biopsy was com- patible with the diagnosis of porphyria cutanea tarda (PCT). The patient began joint follow-up with dermatology. However, his lesions became worse (especially on his upper limbs) and were associated with severe joint pain. In July 2017, it was decided to start treatment with chloroquine, with improve- ment of the lesions and pain until he became asymptomatic.