Six-Month Angiographic Follow-up after Intravascualr Ultrasound Guided Stenting of Infarct Related Artery

摘要

Background and Objectives Intracoronary Stenting has been established as an effective treatment modality for the reduction of restenosis in patients with acute myocardial infarction. This study was performed in order to evaluate the long-term outcomes of stenting for infarct-related artery (IRA) lesions using intravascular ultrasound (IVUS) and compare these results with the stenting of non infarct-related artery (non-IRA) lesions. Subjects and Methods IVUS-guided coronary stenting was successfully performed in 510 native coronary lesions (105 IRA vs. 405 non-IRA). A six-month angiography was performed in 419 lesions (82.2%):87 IRA lesions (82.9%) and 332 non-IRA lesions (82.0%). The results were evaluated using clinical, angiographic and IVUS methods. Results There were no significant differences in the clinical and angiographic variables between the two groups. IVUS variables including reference vessel area and minimal stent area were also similar between the two groups. There was no significant difference in the angiographic restenosis rate between the two groups in cases of minimal stent area 2:12.8% (6/47) in IRA vs. 19.1% (33/173) in non-IRA lesions (p=0.315). However, the angiographic restenosis rate in cases of minimal stent area 2 was 50% (20/40) in IRA lesions vs. 31.5% (50/159) in non-IRA lesions (p=0.028). Conclusion The rate of angiographic restenosis is significantly higher in stenting for IRA lesions as compared with that for non-IRA lesions in cases of minimal stent area 2.