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Infección por VPH y su correlación clínica en población indígena de la región altoandina del Ecuador

机译:厄瓜多尔安第斯山高地区土著居民的HPV感染及其临床相关性

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Cervical-uterine cancer (CaCu) is a public health problem. Epidemiological studies have identified a close relationship between CaCu and human papillomavirus (HPV) infection. The purpose of this study was to perform the molecular detection of HPV, identification of mixed infections and the screening of CaCu through conventional cytology in an indigenous population of the high Andean highlands of Ecuador in order to correlate the data obtained with the presence of lesions. Methodology: A cross-sectional study was carried out on 189 women between the ages of 21 and 65; who belonged to the community of Pilahuin in the province of Tungurahua, who assisted to gynecological check-ups. Data were analyzed with the EPI-INFO and SPSS statistical programs. Results: the average age of the participants was 35.2 years, most of the participants identified themselves as indigenous, in a stable relationship, multiparous, with a medium to low level of education and no paid work. The participants showed a favorable attitude towards the cervico-uterine cytology in 100% of the cases without showing a relation with age, level of education or civil status. HPV infection was positive in 10.5% of the participants, 70% of the patients had severe inflammation with a positive association with mixed bacterial infection.
机译:宫颈子宫癌(CaCu)是一个公共卫生问题。流行病学研究已确定CaCu与人乳头瘤病毒(HPV)感染之间存在密切关系。这项研究的目的是对厄瓜多尔高安第斯高原的土著人口进行HPV分子检测,混合感染鉴定和通过常规细胞学筛查CaCu,以使获得的数据与病变的存在相关联。方法:对189位年龄在21至65岁之间的女性进行了横断面研究;他们属于通古拉瓦(Tungurahua)省的皮拉韦因(Pilahuin)社区,曾协助妇科检查。使用EPI-INFO和SPSS统计程序分析数据。结果:参与者的平均年龄为35.2岁,大多数参与者将自己确定为土著,关系稳定,多方面,教育程度中等至低下,没有带薪工作。在100%的病例中,参与者对宫颈子宫细胞学表现出良好的态度,而与年龄,受教育程度或公民身份无关。 HPV感染在10.5%的参与者中为阳性,其中70%的患者患有严重的炎症,与混合细菌感染呈正相关。

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