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Endovascular Stent Placement for Hemodialysis Arteriovenous Access Stenosis

机译:血液透析动静脉通路狭窄的血管内支架置入

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This study aims to report the outcomes of nitinol and polytetrafluoroethylene covered stent placement to treat hemodialysis arteriovenous access stenosis at a single center over a five-year period. Clinical and radiological information was reviewed retrospectively. Poststent primary and secondary patency rates were determined using Kaplan-Meier analysis. Ten clinical variables were subjected to multivariate Cox regression analysis to determine predictors of patency after stent placement. During the study period 60 stents were deployed in 45 patients, with a mean follow-up of 24.5 months. The clinical and anatomical success rate was 98.3% (59/60). Poststent primary patency rates at 6, 12, and 24 months were 64%, 46%, and 35%, respectively. Poststent secondary patency rates at 6, 12, and 24 months were 95%, 89%, and 85%, respectively. Stent placement for upper arm lesions and in access less than 12 months of age was associated with reduced primary patency (adjusted hazards ratio [HR] 5.1,p=0.0084, and HR 3.5,p=0.0029, resp.). Resistant or recurrent stenosis can be successfully treated by endovascular stent placement with durable long-term patency, although multiple procedures are often required. Stent placement for upper arm lesions and in arteriovenous access less than 12 months of age was associated with increased risk of patency loss.
机译:这项研究旨在报告镍钛诺和聚四氟乙烯覆盖的支架放置在五年内在单个中心治疗血液透析动静脉通路狭窄的结果。临床和放射学信息进行了回顾性审查。使用Kaplan-Meier分析确定支架后的通畅率。对十个临床变量进行多元Cox回归分析,以确定放置支架后通畅的预测指标。在研究期间,在45例患者中部署了60个支架,平均随访24.5个月。临床和解剖学成功率为98.3%(59/60)。在第6、12和24个月时,术后支架的通畅率分别为64%,46%和35%。术后6、12和24个月的术后二次通畅率分别为95%,89%和85%。上臂病变的支架置入和小于12个月的入路与原发通畅性降低相关(调整后的危险比[HR] 5.1,p = 0.0084,HR 3.5,p = 0.0029,分别)。抵抗性或复发性狭窄可通过血管内支架置入术成功治疗,并具有持久的长期通畅性,尽管通常需要多次手术。上臂病变的支架放置以及小于12个月大的动静脉通路与通畅性丧失风险增加相关。

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