Impact of reperfusion therapy and infarct localization on frequency of premature ventricular beats in acute myocardial infarction

摘要

Aim To determine the impact of infarct localization and types ofreperfusion therapy on the frequency of ventricular premature beats(VPBs) in patients with acute myocardial infarction (AMI) andreduced left ventricular ejection fraction (LVEF).Methods A total of 705 patients with acute ST elevation myocardialinfarction (STEMI) were divided according to the infarctlocalization (anteroseptal, anterolateral, inferior and posterior)and reperfusion therapy (fibrinolysis or percutaneous coronaryintervention with stenting) into two groups: LVEF45% was a control group. Theoccurrence of VPBs10 per hour defined as a significant.Results In patients with fibrinolysis therapy and LVEF<45% significantnumber of VPBs were in anteroseptal (p=0.017), anterolateral(p<0.001) and posterior AMI (p<0.001), but in patients withpercutaneous coronary intervention (PCI) and LVEF<45% significantnumber of VPBs were only in anteroseptal AMI (p=0.001)localization.Conclusion In patients with reduced ejection fraction in AMI, treatmentwith PCI method has a better antiarrhythmic effect comparedto fibrinolysis treatment