Evaluation of osteoporotic fractures in the group of woman over 50 years of age – Comparison of tools FRAX? BMD versus FRAX? BMI

摘要

Background: The aim of the project is to identify the risk of osteoporotic fractures in women aged over 50, the evaluation of FRAX? BMD and FRAX? BMI in women with and without osteoporotic fractures and the proposal of therapeutic starting points for treatment of osteoporosis. Material and Methods: A group of 1014 women aged 50-89, living in the Kujawsko-Pomorskie province, was investigated. The analysis was based on the WHO definition of osteoporosis. Calculations of 10-year absolute risk of major osteoporotic fractures (AR-10 MOF Fx) and femoral neck fractures (AR-10 FN Fx) were done using Polish 3.3 version of FRAX? tool. The analysis of fracture risk employed the logistic regression method. Results: A statistically significant relationship was found between the risk of osteoporotic fractures and age, femoral neck BMD, a history of previous osteoporotic fractures, estimated calcaneal BMD and vertebral column BMD. The differences between 10-year absolute risk of major osteoporotic fractures BMD and BMI was small, which means that FRAX? BMI might be a useful tool for GPs and occupational medicine specialists. Conclusions: A high usefulness of the FRAX? BMI tool for evaluating the risk of major osteoporotic fractures provide a new possibility of identifying women at risk of such events. The mean value of 10-year absolute risk of major osteoporotic fractures for FRAX? BMD and BMI was identified as 10% and 12%, respectively and these values were proposed as therapeutic starting points for treatment of osteoporosis in women living in the Kujawsko-Pomorskie province. Med Pr 2013;64(3):327–333