Influence of extremely low frequency magnetic field on total protein and –SH groups concentrations in liver homogenates

摘要

Background: Free radicals are atoms, molecules or their fragments, whose excess leads to the development of oxidative stress, thecause of many neoplastic, neurodegenerative and inflammatory diseases, as well as aging of organisms. Industrial pollution, tobaccosmoke, ionizing radiation, ultrasound and magnetic fields are the major exogenous sources of free radicals. The low frequency magneticfield is commonly applied in physiotherapy. The aim of the present study was to evaluate the effect of extremely low frequencymagnetic field (ELF-MF) on the concentration of sulfhydryl groups (–SH) and proteins in liver tissues of experimental animals dependingon the time of exposure to the field. Material and Methods: Twenty one Sprague-Dawley male rats, aged 3–4 months wererandomly divided into 3 experimental groups (each containing 7 animals): controls (group I), the rats exposed to ELF-MF of 40 Hz,7 mT (this kind of the ELF-MF is mostly used in magnetotherapy), 30 min/day for 2 weeks (group II) and the rats exposed to 40 Hz,7 mT for 60 min/day for 2 weeks (group III). The concentrations of proteins and sulfhydryl groups in the liver tissues were determinedafter exposure to magnetic fields. Results: Exposure to low magnetic field: 40 Hz, 7 mT for 30 min/day and 60 min/day for 2 weekscaused a significant increase in the concentration of –SH groups and total protein levels in the liver tissues. Conclusions: The studyresults suggest that exposure to magnetic fields leads to the development of adaptive mechanisms to maintain the balance in the bodyoxidation-reduction and in the case of the studied parameters does not depend on the time of exposure. Med Pr 2014;65(5):639–644