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“Star” suture opacities of the crystalline lens: an illustrative report in AIDS patients

机译:晶状体的“星形”缝合混浊:艾滋病患者的说明性报告

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Background:Acquired immunodeficiency syndrome (AIDS) is disease of epidemic proportion associated with significant visual morbidity. Visual complications of AIDS have been described as a result of cytomegaloviral retinitis as well as fungal and protozoan opportunistic eye disease. Although cataracts have been established as a direct consequence of human immunodeficiency virus (HIV) or AIDS, studies suggest that HIV disease may indeed be a risk factor for the development of cortical cataract. This report further characterizes potential lens abnormalities associated with HIV and AIDS by clearly demonstrating opacities associated with lens sutures in two AIDS patients with long-term use of nucleoside analogue reverse transcriptase inhibitors (NRTIs).Material/Methods:Case series demonstrating digitized slit lamp biomicroscopic anterior segment photos using indirect lens illumination.Results:Prominent “star” lens sutures of assumed abnormality typified by unusual branching and irregular caliber are photo-documented.Conclusions:Normally inconspicuous star suture branches are clearly demonstrated in two patients with AIDS and diabetes mellitus. Uncharacteristic star lens sutures have not been previously reported in AIDS patients however the occurrence of lens opacities due to HIV disease and AIDS is not without precedent. Despite the prominence and atypical nature of the illustrated lens sutures, assessment of morphologic abnormality is limited by lack of appropriate normative data describing star sutures clinically as a function of age and lens development.
机译:背景:获得性免疫缺陷综合症(AIDS)是一种流行病,伴有明显的视觉疾病。据描述,爱滋病的视觉并发症是巨细胞病毒性视网膜炎以及真菌和原生动物机会性眼病的结果。尽管已经确定白内障是人类免疫缺陷病毒(HIV)或AIDS的直接后果,但研究表明,HIV疾病确实可能是皮质白内障发展的危险因素。本报告通过明确证实两名长期使用核苷类似物逆转录酶抑制剂(NRTIs)的AIDS患者与晶状体缝线相关的不透明性,进一步表征了与HIV和AIDS相关的潜在晶状体异常。材料/方法:案例系列展示了数字化裂隙灯生物显微镜结果:照片记录了假定异常的突出的“星形”晶状体缝线,以不寻常的分支和不规则的口径为代表。结论:通常在两名患有艾滋病和糖尿病的患者中清楚地显示出不明显的星形缝线。艾滋病患者以前没有报道过不典型的星形晶状体缝线,但是由于艾滋病和艾滋病而导致晶状体混浊的发生并非没有先例。尽管图示的晶状体缝线突出并且具有非典型性质,但是由于缺乏适当的规范性数据,临床上根据年龄和晶状体发育来描述星形缝线,因此形态异常的评估受到限制。

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