Local extensive granulomatous inflammation of the neck region and lymphangitis caused by Lichtheimia corymbifera infection in a Japanese Black calf

摘要

A 7-month-old female Japanese Black calf developed elongated, nodular mass measuring 30?×?16?cm extended from the retropharyngeal region to mid lateral neck region. Histological examination revealed granulomatous lymphangitis with non-septate fungal hyphae recognized throughout the lesions. Fungal culture, DNA sequencing and molecular phylogenetic tree analysis confirmed the sequence of Lichtheimia corymbifera . The lymphogenous route was speculated to be the main route of fungal spread leading to the characteristic nodular appearance of this case.