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P-Values: Misunderstood and Misused

机译:P值:被误解和滥用

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P-values are widely used in both the social and natural sciences to quantify the statistical significance of observed results. The recent surge of big data research has made the p-value an even more popular tool to test the significance of a study. However, substantial literature has been produced critiquing how p-values are used and understood. In this paper we review this recent critical literature, much of which is routed in the life sciences, and consider its implications for social scientific research. We provide a coherent picture of what the main criticisms are, and draw together and disambiguate common themes. In particular, we explain how the False Discovery Rate is calculated, and how this differs from a p-value. We also make explicit the Bayesian nature of many recent criticisms, a dimension that is often underplayed or ignored. We conclude by identifying practical steps to help remediate some of the concerns identified. We recommend that (i) far lower significance levels are used, such as 0.01 or 0.001, and (ii) p-values are interpreted contextually, and situated within both the findings of the individual study and the broader field of inquiry (through, for example, meta-analyses).
机译:P值在社会科学和自然科学中被广泛使用,以量化观察结果的统计意义。最近的大数据研究热潮使p值成为检验一项研究重要性的一种更流行的工具。但是,已经出现了大量有关如何使用和理解p值的文献。在本文中,我们回顾了这些最近的批判性文献,其中许多文献是在生命科学中提出的,并考虑了其对社会科学研究的影响。我们提供了有关主要批评内容的连贯图片,并汇集并消除了共同主题的歧义。特别是,我们解释了错误发现率的计算方式以及它与p值的区别。我们还明确指出了许多最近批评的贝叶斯性质,这一方面经常被低估或忽略。最后,我们通过确定一些实际步骤来帮助纠正一些已确定的问题。我们建议(i)使用低得多的显着性水平,例如0.01或0.001,并且(ii)p值是根据上下文进行解释的,并且位于单个研究的发现和更广泛的研究领域中(通过例如荟萃分析)。

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