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Indigenous Perspectives and Gene Editing in Aotearoa New Zealand

机译:新西兰Aotearoa的土著观点和基因编辑

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Gene editing is arguably the most significant recent addition to the modern biotechnology toolbox, bringing both profoundly challenging and enabling opportunities. The specificity of these new tools and the relative simplicity of use, from a technical point of view, have broadened the potential applications and re-ignited the ethical debates generated by earlier forms of genetic modification. In New Zealand gene editing is currently considered genetic modification and is subject to approval processes under the Environmental Protection Authority (EPA), which requires the consideration of Māori perspectives. This article outlines previously articulated Māori perspectives on genetic modification, considers the continuing influence of those cultural and ethical arguments within the new context of gene editing, and explores with key Maori informants how cultural values might be used to analyse the risks and benefits of gene editing in the Aotearoa New Zealand context. Methods used to obtain these perspectives consisted of (a) review of relevant literature regarding lessons learned from the responses of Maori to genetic modification, (b) interviews of selected ‘key Maori informants’ and (c) surveys of self-selected individuals from groups with interests in either genetic or environmental management. The results of this pilot study identified that while Māori informants were not categorically opposed to new and emerging gene editing technologies a priori, they suggest a dynamic approach to regulation is required where specific uses or types of uses are approved on a case by case basis. This study demonstrates how the cultural cues that Māori referenced in the genetic modification debate, and subsequent conversations about biotechnologies, continue to be relevant in the context of gene editing.
机译:基因编辑可以说是现代生物技术工具箱中最重要的最新功能,既带来了巨大的挑战,也带来了机遇。从技术的角度来看,这些新工具的特殊性和相对简单的使用,拓宽了潜在的应用范围,并重新点燃了由早期遗传修饰形式引发的伦理争议。在新西兰,基因编辑目前被认为是遗传修饰,需要经过环境保护局(EPA)的批准程序,这需要考虑毛利人的观点。本文概述了以前表达的毛利人对基因改造的观点,考虑了这些文化和伦理论点在基因编辑新背景下的持续影响,并与毛利人的主要信息提供者探讨了如何使用文化价值来分析基因编辑的风险和利益在新西兰的Aotearoa中。获得这些观点的方法包括:(a)回顾有关从毛利人对基因改造的反应中汲取的教训的相关文献;(b)采访选定的“重要毛利人信息提供者”;以及(c)对群体中自我选择的个人进行调查对遗传或环境管理感兴趣。这项前瞻性研究的结果表明,尽管毛利线人并不绝对反对先验和新兴的基因编辑技术,但他们建议,在逐案批准特定用途或用途类型的情况下,需要一种动态的监管方法。这项研究表明,毛利人在基因改造辩论以及随后有关生物技术的讨论中所引用的文化线索在基因编辑的背景下如何继续发挥作用。

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