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NEURONAL SIGNALING

机译:神经信号

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摘要

Intracellular processes in neurons begins when the extracellular chemical signals such as neurotransmitters, attached at specific receptors which then activates a cascade of intracellular reactions included herein are proteins GTP, second messengers, protein kinases, ion channels, and other effector proteins that will change the instantaneous state of the physiology of the cell the target. The intracellular signal will also change the long-term performance by interfering with the transcription of genes that will change the protein composition of the target cell. Many components are involved in intracellular signal that will control the neurons, so that the necessary coordination of electrical and chemical signals in the nervous system. Also discussed here regarding the conducting various signals in neurons, including signaling pathways, type receptors, G proteins and molecular targets, second messengers, the target of second messengers, NGF/TrkA, long-term depression (LTD), and tyrosine phosphorylation hidrosilase.
机译:当附着在特定受体上的细胞外化学信号(例如神经递质)随后激活此处包括的一系列细胞内反应时,神经元的细胞内过程开始,这些蛋白包括GTP蛋白质,第二信使,蛋白激酶,离子通道和其他会改变瞬时信号的效应蛋白。靶细胞的生理状态。细胞内信号还将通过干扰将改变靶细胞蛋白质组成的基因的转录来改变长期性能。细胞内信号涉及许多成分,这些成分将控制神经元,因此神经系统中电信号和化学信号的必要协调。本文还讨论了在神经元中传导各种信号的问题,包括信号传导途径,类型受体,G蛋白和分子靶标,第二信使,第二信使的靶标,NGF / TrkA,长期抑郁症(LTD)和酪氨酸磷酸化Hidrosilase。

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