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首页> 外文期刊>Frontiers in Cellular Neuroscience >Androstenediol Reduces Demyelination-Induced Axonopathy in the Rat Corpus Callosum: Impact on Microglial Polarization
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Androstenediol Reduces Demyelination-Induced Axonopathy in the Rat Corpus Callosum: Impact on Microglial Polarization

机译:二十碳二烯二醇减少大鼠Corp体中脱髓鞘诱导的轴索病:对小胶质细胞极化的影响。

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Aims: We have previously shown that the neurosteroid androstenediol (ADIOL) promotes remyelination following gliotoxin-induced demyelination. However, the impact of this ADIOL on axonal recovery is not yet known. In the present study, we investigated the impact of ADIOL on axonal integrity following a focal demyelination in the corpus callosum.
机译:目的:我们先前已经证明神经甾体雄烯二醇(ADIOL)会在胶体毒素诱导的脱髓鞘后促进髓鞘再生。然而,这种ADIOL对轴突恢复的影响尚不清楚。在本研究中,我们调查了call体局灶性脱髓鞘后ADIOL对轴突完整性的影响。

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