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Multidisciplinary approach to manage antenatally suspected placenta percreta: updated algorithm and patient outcomes

机译:多学科方法来管理产前可疑胎盘穿孔:更新的算法和患者预后

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BackgroundDue to the significant morbidity and mortality associated with placenta percreta, alternative management options are needed. Beginning in 2005, our institution implemented a multidisciplinary strategy to patients with suspected placenta percreta. The purpose of this study is to present our current strategy, maternal morbidity and outcomes of patients treated by our approach. MethodsFrom 2005 to 2014, a retrospective cohort study of patients with suspected placenta percreta at an academic tertiary care institution was performed. Treatment modalities included immediate hysterectomy at the time of cesarean section (CHYS), planned delayed hysterectomy (interval hysterectomy 6?weeks after delivery) (DH), and fertility sparing (uterine conservation) (FS). Prognostic factors of maternal morbidity were identified from medical records. Complications directly related to interventional procedures and DH was recorded. Descriptive statistics were utilized. ResultsOf the 21 patients with suspected placenta percreta, 7 underwent CHYS, 13 underwent DH, and 1 had FS with uterine preservation. Of the 20 cases that underwent hysterectomy, final pathology showed 11 increta, 7 percreta, and 2 inconclusive. 19/20 cases underwent interventional radiology (IR) procedures. Selective embolization was utilized in 14 cases (2/7 CHYS; 12/13 DH). The median time from cesarean section (CS) to DH was 41 [26–68] days. There were no cases of emergent hysterectomy, delayed hemorrhage, or sepsis in the DH group. Both estimated blood loss and number of packed red blood cell transfusions were significantly higher in the CHYS group. 3/21 cases required massive transfusion (2 CHYS, 1 FS) with median total blood product transfusion of 13?units [12–15]. The four IR-related complications occurred in the DH group. Incidence of postoperative complications was similar between both groups. Median hospital length of stay (LOS) after CHYS was 4?days [3–8] compared to DH cohort: 7?days [3–33] after CS and 4?days [1 –10] after DH. The DH cohort had a higher rate of hospital readmission of 54% (7/13) compared to 14% (1/7) CHYS, most commonly due to pain. There were no maternal deaths. ConclusionThis multidisciplinary strategy may appear feasible; however, further investigation is warranted to evaluate the effectiveness of alternative approaches to cesarean hysterectomy in cases of morbidly adherent placenta.
机译:背景技术由于与胎盘穿孔相关的高发病率和高死亡率,因此需要其他治疗方案。从2005年开始,我们机构对疑似胎盘穿孔的患者实施了多学科策略。这项研究的目的是介绍我们目前的策略,孕产妇发病率以及通过我们的方法治疗的患者的结局。方法2005年至2014年,在一家三级学术机构对一项疑似胎盘穿孔的患者进行了回顾性队列研究。治疗方式包括剖宫产时立即行子宫切除术(CHYS),计划的延迟子宫切除术(分娩后6周进行间隔子宫切除术)(DH)和保留生育力(保留子宫)(FS)。从病历中确定了孕产妇发病的预后因素。记录与介入手术和DH直接相关的并发症。使用描述性统计。结果21例疑似胎盘穿孔的患者中,有7例行CHYS,13例行DH,其中1例行FS保胎。在20例行子宫切除术的病例中,最终病理显示11例,7例和2例不确定。 19/20例患者接受了放射介入治疗。选择性栓塞治疗14例(2/7 CHYS; 12/13 DH)。从剖宫产(CS)到DH的中位时间为41 [26-68]天。 DH组无急诊子宫切除术,延迟出血或败血症病例。 CHYS组的估计失血量和大量红细胞输注量均明显更高。 3/21例需要大量输血(2 CHYS,1 FS),输血中位数为13?单位[12-15]。 DH组发生了4种与IR相关的并发症。两组的术后并发症发生率相似。与DH组相比,CHYS后中位住院天数(LOS)为4天[3-8]:CS后7天[3–33]和DH后4天[1-10]。 DH组的住院再入院率较高,为54%(7/13),而CHYS为14%(1/7),最常见的原因是疼痛。没有孕产妇死亡。结论这种多学科策略可能是可行的。但是,有必要进行进一步的研究以评估在病态粘附的胎盘情况下进行剖宫产子宫切除术的替代方法的有效性。

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