Complications after Fusion for Thoracolumbar Fractures in Patients with Ankylosing Spondylitis

摘要

Study Design Retrospective analysis of a Medicare database (2005 to 2012). Objective To study postoperative complication rates following thoracolumbar fusion for traumatic thoracolumbar fracture in patients with ankylosing spondylitis (AS) compared with patients without AS. Methods The PearlDiver database (2005 to 2012) was queried to examine postoperative complication rates in patients with AS undergoing posterior thoracolumbar fusion for thoracolumbar fracture ( n = 968). Complication rates were compared with proportion-matched controls without AS undergoing the same procedure ( n = 1,979). We examined and compared the incidence of death, postoperative infection, transfusion, venous thromboembolism, respiratory failure, pneumonia, myocardial infarction, urinary tract infection, and acute renal failure in each cohort within 90 days postoperatively. Results Patients with AS had significantly higher rates of surgical site infection (odds ratio [OR] 1.6, 95% confidence interval [CI] 1.2 to 2.2, p = 0.002), day-of-surgery transfusion rates (OR 1.5, 95% CI 1.3 to 1.8, p