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Combined modified en bloc corpectomy with replacement of the aorta in curative interdisciplinary treatment of a large osteosarcoma infiltrating the aorta

机译:改良整块体切除术联合主动脉置换在根治性大骨肉瘤的根治性跨学科治疗中

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PurposeWe report a case of a large three-level spinal osteosarcoma infiltrating the adjacent aorta. This is the first case in which a combined modified three-level en bloc corpectomy with resection and replacement of the adjacent aorta was successful as a part of interdisciplinary curative treatment.MethodsCase report.ResultsThe surgical procedure was performed as a two-step treatment. A heart lung machine (HLM) was not used, in order to avoid cerebral and spinal ischemia and to decrease the risk of hematogenous tumor metastases. Instead, a bypass from the left subclavian artery the distal descending aorta was used. We modified the en bloc corpectomy procedure, leaving a dorsal segment of the vertebral bodies to enable rapid surgery. The procedure was successful and the en bloc resection of the vertebral body with aortal resection could be achieved. Except for pallhypesthesia in the left dermatomes Th7–Th10, the patient does not have any postoperative neurologic deficits.ConclusionCombined corpectomy with aortic replacement should be considered as a reasonable option in the curative treatment of osteosarcoma with consideration of the immense surgical risks. The use of an HLM is not necessary, especially considering the inherent risk of hematogenous tumor metastases. Modified corpectomy leaving a dorsal vertebral body segment was considered a reasonable variation since tumor-free margins could still be expected...
机译:目的我们报告一例大型三级脊柱骨肉瘤浸润邻近主动脉的病例。这是首次将改良的三级整块切除术与邻近主动脉切除和置换相结合作为跨学科治愈性治疗的一部分获得成功。方法病例报告。不使用心肺机(HLM),以避免脑部和脊髓缺血并降低发生血源性肿瘤转移的风险。相反,使用从左锁骨下动脉至远端降主动脉的旁路。我们修改了整体体切除术的程序,保留了椎体的背节以进行快速手术。该过程是成功的,并且可以实现椎体整体切除和主动脉切除。除左皮层Th7–Th10的睑下垂症外,患者无任何术后神经功能缺损。结论考虑到巨大的手术风险,在骨肉瘤的根治性治疗中,应考虑将联合体切除术与主动脉置换术相结合。无需使用HLM,尤其是考虑到血源性肿瘤转移的固有风险。改良的椎体切除术离开椎体后段被认为是合理的变异,因为仍然可以期待无肿瘤的边缘...

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