Periodontal health status in patients treated with the Invisalign? system and fixed orthodontic appliances: A 3 months clinical and microbiological evaluation

摘要

Objective:The aim of this prospective study was to compare the periodontal health and the microbiological changes via real-time polymerase chain reaction (PCR) in patients treated with fixed orthodontic appliances and Invisalign? system (Align Technology, Santa Clara, California).Materials and Methods:Seventy-seven patients were enrolled in this study and divided into three groups (Invisalign? group, fixed orthodontic appliances group and control group). Plaque index, probing depth, bleeding on probing were assessed. Total biofilm mass and periodontal pathogens were analyzed and detected via real-time PCR. All these data were analyzed at the T0 (beginning of the treatment) T1 (1-month) and T2 (3 months); and statistically compared using the Mann–Whitney test for independent groups.Results:After 1-month and after 3 months of treatment there was only one sample with periodontopathic anaerobes found in patient treated using fixed orthodontic appliances. The Invisalign? group showed better results in terms of periodontal health and total biofilm mass compared to the fixed orthodontic appliance group. A statistical significant difference (P < 0.05) at the T2 in the total biofilm mass was found between the two groups.Conclusion:Patients undergoing orthodontic treatment with the Invisalign? System show a superior periodontal health in the short-term when compared to patients in treatment with fixed orthodontic appliances. Invisalign? should be considered as a first treatment option in patients with risk of developing periodontal disease.