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In-home solid fuel use and cardiovascular disease: a cross-sectional analysis of the Shanghai Putuo study

机译:家用固体燃料的使用与心血管疾病:上海普陀研究的横断面分析

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Background Although recent research evidence suggests an association between household air pollution from solid fuel use, such as coal or biomass, and cardiovascular events such as hypertension, little epidemiologic data are available concerning such exposure effects on cardiovascular endpoints other than hypertension. We explored the association between in-home solid fuel use and self-reported diagnoses of cardiovascular endpoints, such as hypertension, coronary heart disease (CHD), stroke, and diabetes. Methods We analyzed 14,068 Chinese adults, aged 18 years and older. Odds ratios (OR) and the corresponding 95% confidence intervals (CI) were estimated using logistic regression models for the risk of each outcome after adjusting for potential confounders. Results The use of solid fuel in home was significantly associated with an increased risk for hypertension (OR 1.70, 95% CI 1.40 to 2.07), CHD (OR 2.58, 95% CI 1.53 to 4.32), and diabetes (OR 2.48, 95% CI 1.59 to 3.86), after adjusting for potential confounders. Compared with individuals in the lowest tertile of the duration of solid fuel exposure, those in the highest tertile of the duration of solid fuel exposure had an increased odds of hypertension (OR 1.73, 95% CI 1.45 to 2.06), stroke (OR 1.87, 95% CI 1.03 to 3.38), and diabetes (OR 3.18, 95% CI 2.11 to 4.78). Conclusions Our data suggest that in-home solid fuel exposure maybe associated with increased risk for hypertension, CHD, stroke, and diabetes in the Chinese adult population. Further large-scale longitudinal studies are warranted to confirm these findings.
机译:背景技术尽管最近的研究证据表明,使用固体燃料(例如煤或生物质)造成的家庭空气污染与心血管事件(例如高血压)之间存在关联,但很少有流行病学数据涉及此类暴露对高血压以外的心血管终点的影响。我们探索了家庭固体燃料的使用与心血管疾病(例如高血压,冠心病(CHD),中风和糖尿病)的自我报告的诊断之间的关联。方法我们分析了14068名年龄在18岁以上的中国成年人。校正潜在混杂因素后,使用逻辑回归模型估算每种结果风险的几率(OR)和相应的95%置信区间(CI)。结果在家中使用固体燃料与高血压(OR 1.70,95%CI 1.40至2.07),CHD(OR 2.58,95%CI 1.53至4.32)和糖尿病(OR 2.48,95%)的发生风险显着相关CI(1.59至3.86),经过对潜在混杂因素的调整后。与处于固体燃料暴露持续时间最低的三分位数的人相比,处于固体燃料暴露持续时间的最高三分位数的人的高血压(OR 1.73,95%CI 1.45至2.06),中风(OR 1.87, 95%CI为1.03至3.38)和糖尿病(OR 3.18,95%CI为2.11至4.78)。结论我们的数据表明,在中国成年人体内,家庭固体燃料的暴露可能与高血压,冠心病,中风和糖尿病的风险增加有关。有必要进行进一步的大规模纵向研究来证实这些发现。

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