Occurrence and Ecotoxicological Risk Assessment of Analgesics in Wastewater

摘要

In this study, concentrations of analgesics including acetaminophen (ACETAM), indomethacin (INDO), acetylsalicylic acid (ACETYL ACID), phenylbutazone (PHENYL) and codeine (CO) were determined in wastewaters and risk assessment for organisms in the receiving environment was carried out. The analytical method for determination of analgesics in wastewater was optimized. The detection of analgesics was carried out by HPLC-MS/MS. Limit of detection (LOD) values for studied compounds were determined between 0.017 and 0.197 μg/L. Wastewater samples were taken from Konya Urban Wastewater Treatment Plant influent and effluent. ACETAM, CO, and INDO compounds were determined as 13000, 150, 80 ng/L in influent samples, respectively. ACETYL ACID and PHENYL were determined below limit of detection in influent samples. While INDO was determined about 84ng/L in effluent samples, ACETAM and CO were determined up to 25ng/L. The analgesic compounds indicated insignificant risk for algae, Daphnia magna and fish in the receiving environment.