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Factors associated with prolonged length of stay in patients admitted with severe hypoglycaemia to a tertiary care hospital

机译:患有严重低血糖症的三级住院患者的住院时间延长的相关因素

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Severe hypoglycaemia carries considerable morbidity and potential mortality. We aim to elucidate the factors which were associated with a prolonged length of stay (LOS) among patients with diabetes who were admitted to the hospital with severe hypoglycaemia. Three hundred and four patients were included in the analysis, with a mean age of 70.6?±?11.3?years, mean glycated haemoglobin of 6.9?±?1.3% and median LOS of 3?days. Patients with a LOS 3?days had significantly higher Charlson Comorbidity Index (CCI) (4.9?±?2.1 vs 4.1?±?2.1, P ?0.01), a lower glomerular filtration rate (GFR) (34.6?±?31.4?mL/min vs 44.8?±?28.9?mL/min, P =?0.01) and a higher proportion of these patients suffered from recurrent hypoglycaemia during the admission (38.9% vs 27.7%, P =?0.04). In addition, they had higher white cell counts (11.1?±?4.8?×?10sup9/sup/L vs 9.3?±?3.2?×?10sup9/sup/L) and lower albumin concentrations (32.9?±?6.6?g/L vs 36.8?±?4.9?g/L). Bivariate analysis showed that the same factors were associated with prolonged LOS. Identification of risk factors associated with prolonged LOS provides the opportunity for intervention to reduce the LOS and improve the outcomes for these patients.
机译:严重的低血糖症会导致较高的发病率和潜在的死亡率。我们的目的是阐明那些因严重低血糖而入院的糖尿病患者的住院时间延长(LOS)相关的因素。该分析纳入了304例患者,平均年龄为70.6±11.3岁,平均糖化血红蛋白为6.9±1.3%,中位LOS为3天。 LOS> 3天的患者的Charlson合并症指数(CCI)显着更高(4.9±±2.1 vs 4.1±±2.1,P <0.01),肾小球滤过率(GFR)较低(34.6±±31.4) ?mL / min比44.8?±?28.9?mL / min,P =?0.01),并且这些患者中入院时复发性低血糖的比例更高(38.9%比27.7%,P =?0.04)。此外,他们的白细胞计数更高(11.1±±4.8?×?10 9 / L与9.3?±?3.2?×?10 9 / L)以及较低的白蛋白浓度(32.9?±?6.6?g / L与36.8?±?4.9?g / L)。双变量分析表明,相同的因素与LOS延长有关。与长期LOS相关的危险因素的识别为减少这些LOS和改善这些患者的预后提供了机会。

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