Cardiac troponin T in neonates with respiratory distress

摘要

ObjectiveThe purpose of this study is to assess cardiac troponin T(cTnT) in neonates with respiratory distress as a marker of myocardial dysfunction.Study DesignEighty neonates with respiratory distress and 20 healthy infants were included in the study. Patients were subdivided into 4 groups according to the etiology. Serum cardiac troponin T was measured using ELISA technique.ResultsCardiac troponin T levels were significantly higher (p?=?0.001) in neonates with respiratory distress (0.041?±?0.02?ng/ml) compared with controls(0.022?±?0.012). Infants with respiratory distress syndrome had the highest cTnT levels (0.043?±?0.022?ng/ml), while those with transient tachypnea had the lowest levels (0.036?±?0.017?ng/ml). Also, cTnT levels were significantly higher in neonates who required inotropic support when compared to those without inotropes. We did not find statistically significant differences between survivors and non-survivors.ConclusionCardiac troponin T is higher in neonates with respiratory distress compared to healthy infants. It could be used as a useful marker for myocardial dysfunction.